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South America Cruises April 2021

Save up to 75% on South America Cruises April 2021

As a large-scale seller of South America Cruises April 2021, we are able to offer you unbeatable prices and unparalleled value. With cruise line volume buys plus our low everyday prices you can save up to 75% versus the brochure price! Once you have found the discounted South America cruise of your choice, please call our cruise consultants to book your vacation and save money with our first-rate personalized service! Book your South America cruise today with AffordableTours.com, your discounted cruise headquarters.

Learn more about South America Cruises

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Sail Date Cruise Line Ship Destination Departs Length Price You Save Discounts
116 reviews
Itinerary Map/Ship Image
Holland AmericaWesterdamSouth AmericaBuenos AiresSan Antonio14 Nights
-100%
From: $9,999,999
You Save: $9,998,300
Up To $300 Onboard Credit
Onboard Credit!
31 reviews
Itinerary Map/Ship Image
RegentSeven Seas NavigatorSouth AmericaMiamiMiami25 NightsAlter Do Chao (Amazon River) | Basseterre | Boca Da Valeria (Amazon River) | Bridgetown | Castries | Gustavia | Macapa (Amazon River) | Manaus (Amazon River) | Miami | Parintins (Amazon River) | Pointe A Pitre | Port Of Spain | Puerto Plata | San Juan | Santarem (Amazon River) | St. George's
-63%
From: $29,598
You Save: $18,599
Up To $1000 Onboard Credit
62%
Suite!
Itinerary Map/Ship ImageVikingSanta Cruz IIGalapagosBaltraBaltra14 NightsBaltra, Ecuador | Espanola Island, Ecuador | Mosquera Islet, Ecuador | Santa Fe Island, Ecuador$10,499 
10 reviews
Itinerary Map/Ship Image
Celebrity XpeditionGalapagosBaltraBaltra7 NightsBaltra, Galapagos | Bartalome, Galapagos | Black Turtle Cove (santa | Caleta Tagus, Galapagos | Daphne Island | Darwin Bay (genovesa) | El Barranco (genovesa) | Las Bachas, (santa Cruz) | Puerto Ayora, Ecuador | Puerto Egas, Ecuador | Rabida, Ecuador | Urvina Bay (isabella) | Vicente Roca Point$4,649
Up To $200 Onboard Credit
Onboard Credit!

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Itinerary Map/Ship ImageCelebrity XplorationGalapagosBaltraBaltra7 NightsBahia Post Office (floreana) | Baltra, Galapagos | Cerro Brujo (san Cristobal) | Cormorant Point (floreana) | Daphne Island | Dragon Hill (santa Cruz) | Gardner Bay (espa¹ola) | Kicker Rock (san Cristobal) | Los Lobos (san Cristobal) | Mosquera Islet (galapagos) | Puerto Ayora, Ecuador | Puerto Villamil (isabella) | Punta Suarez, Ecuador | Rabida, Ecuador | Wall Of Tears (isabella)$6,723
Up To $200 Onboard Credit
Onboard Credit!
Itinerary Map/Ship ImageSilverseaSilver OriginGalapagosBaltraSan Cristobal7 NightsBahia Sullivan, Santiago | Bahia, Darwin, Genovesa | Baltra, Galapagos | Cerro Brujo (San Cristobal), Galapagos | El Barranco, Genovesa | Gardner Bay (Española), Galapagos | Isla Daphne Grande, Ecuador | North Seymour, Ecuador | Puerto Ayora, Ecuador | Punta Suarez (Espanola), Ecuador, Galapagos | San Cristobal, Ecuador$13,000
Up To $1000 Onboard Credit
 
7 reviews
Itinerary Map/Ship Image
MSC SinfoniaEuropeMontevideoVenice21 NightsBuenos Aires, Argentina | Cadiz, Spain | Dubrovnik, Croatia | Malaga, Spain | Montevideo, Uruguay | Palermo, Italy | Recife, Brazil | Rio de Janeiro, Brazil | Santa Cruz de Tenerife, Spain | Venice, Italy$859
Up To $150 Onboard Credit
Onboard Credit!
Itinerary Map/Ship ImageCelebrity FloraGalapagosBaltraBaltra7 NightsBaltra, Galapagos | Bartalome, Galapagos | Caleta Tagus, Galapagos | Daphne Island | Elizabeth Bay | Las Bachas, (santa Cruz) | North Seymour, Ecuador | Puerto Ayora, Ecuador | Puerto Baquerizo, Ecuador | Puerto Egas, Ecuador | Punta Pitt (san Cristobal) | Rabida, Ecuador | Santiago, Chile$7,999
Up To $200 Onboard Credit
Suite!
7 reviews
Itinerary Map/Ship Image
MSC SinfoniaEuropeBuenos AiresVenice20 NightsBuenos Aires, Argentina | Cadiz, Spain | Dubrovnik, Croatia | Malaga, Spain | Palermo, Italy | Recife, Brazil | Rio de Janeiro, Brazil | Santa Cruz de Tenerife, Spain | Venice, Italy$969
Up To $100 Onboard Credit
Onboard Credit!
2 reviews
Itinerary Map/Ship Image
PonantLe SolealTahitiHanga RoaPapeete13 NightsAdamstown, Pitcairn Island | Hanga Roa, Easter Island | Papeete, Tahiti Island | Rangiroa, Tuamotu Islands$6,080
Up To $750 Onboard Credit
 
114 reviews
Itinerary Map/Ship Image
Celebrity SilhouetteTransatlanticRio De JaneiroLisbon12 NightsLisbon, Portugal | Rio De Janeiro, Brazil | Salvador De Bahia, Brazil | Tenerife, Canary Islands$1,209
Up To $250 Onboard Credit
Onboard Credit!
7 reviews
Itinerary Map/Ship Image
MSC SinfoniaEurope - WesternRio De JaneiroMalaga12 NightsCadiz, Spain | Malaga, Spain | Recife, Brazil | Rio de Janeiro, Brazil | Santa Cruz de Tenerife, Spain$439
Up To $50 Onboard Credit
 
10 reviews
Itinerary Map/Ship Image
Celebrity XpeditionGalapagosBaltraBaltra7 NightsBahia Post Office (floreana) | Baltra, Galapagos | Cormorant Point (floreana) | Elizabeth Bay | Gardner Bay (espa¹ola) | Moreno Point (isabella) | North Seymour, Ecuador | Puerto Ayora, Ecuador | Puerto Baquerizo, Ecuador | Punta Pitt (san Cristobal) | Punta Suarez, Ecuador | Santa Fe Island | South Plaza (santa Cruz)$5,624
Up To $200 Onboard Credit
 
5 reviews
Itinerary Map/Ship Image
Seabourn QuestSouth AmericaManausMiami15 NightsBridgetown, Barbados | Devils Island, French Guiana | Fort-De-France, Martinique | Manaus, Brazil | Miami, Florida | Parintins, Brazil | San Juan, Puerto Rico | Santarem, Brazil | St. Johns, Antigua$6,759
Up To $750 Onboard Credit
Suite!
5 reviews
Itinerary Map/Ship Image
Seabourn QuestTransatlanticManausRotterdam30 NightsBridgetown, Barbados | Cherbourg, France | Devils Island, French Guiana | Fort-De-France, Martinique | Horta | Manaus, Brazil | Miami, Florida | Parintins, Brazil | Ponta Delgada | Rotterdam | San Juan, Puerto Rico | Santarem, Brazil | St. Johns, Antigua | Zeebrugge, Belgium$9,680
Up To $1000 Onboard Credit
 
5 reviews
Itinerary Map/Ship Image
Seabourn OdysseyPanama CanalBridgetownLos Angeles (San Pedro)35 NightsAruba | Bonaire, Netherlands Antilles | Bridgetown, Barbados | Cabo San Lucas, Mexico | Cartagena, Colombia | Curacao, Netherlands | Fuerte Amador, Panama | Grenada | Huatulco, Mexico | Isla Catalina, Dominican Republic | Key West, Florida | Los Angeles (San Pedro) | Miami, Florida | Puerto Chiapas, Mexico | Puerto Quetzal, Guatemala | Punta Arenas, Chile | Rodney Bay | San Juan, Puerto Rico | Santa Marta, Colombia | Santo Domingo, Dom Rep.$13,534
Up To $1000 Onboard Credit
 
4 reviews
Itinerary Map/Ship Image
Norwegian EncorePanama CanalMiamiLos Angeles (San Pedro)16 NightsCabo San Lucas, Mexico | Cartagena Colombia | Colon, Panama | Los Angeles, CA | Miami, FL | Puerto Quetzal, Guatemala | Puerto Vallarta, Mexico | San Diego, CA | Transit Panama Canal, At Sea
-60%
From: $2,882
You Save: $1,723
Up To $250 Onboard Credit
59% 
Itinerary Map/Ship ImageCelebrity FloraGalapagosBaltraBaltra7 NightsBahia Post Office (floreana) | Baltra, Galapagos | Cormorant Point (floreana) | Daphne Island | Dragon Hill (santa Cruz) | Gardner Bay (espa¹ola) | Moreno Point (isabella) | Puerto Ayora, Ecuador | Punta Suarez, Ecuador | South Plaza (santa Cruz) | Urvina Bay (isabella) | Vicente Roca Point$10,049
Up To $200 Onboard Credit
Suite!
90 reviews
Itinerary Map/Ship Image
Holland AmericaNieuw AmsterdamPanama CanalFt. LauderdaleVancouver18 NightsCabo San Lucas, Mexico | Cartagena, Colombia | Corinto, Nicaragua | Ft. Lauderdale, Florida | Huatulco, Mexico | Puerto Chiapas, Mexico | Puerto Quetzal, Guatemala | San Francisco, California | Vancouver, Canada | Victoria, British Columbia$1,499
Up To $250 Onboard Credit
Onboard Credit!
90 reviews
Itinerary Map/Ship Image
Holland AmericaNieuw AmsterdamPanama CanalFt. LauderdaleSan Francisco15 NightsCabo San Lucas, Mexico | Cartagena, Colombia | Corinto, Nicaragua | Ft. Lauderdale, Florida | Huatulco, Mexico | Puerto Chiapas, Mexico | Puerto Quetzal, Guatemala | San Francisco, California$1,249
Up To $250 Onboard Credit
Onboard Credit!

Learn More About South America Cruises

One incredibly popular South America cruise itinerary is to the Galapagos Islands, situated around the equator about 600 miles off the coast of continental Ecuador. Here reside dozens of birds, reptiles, amphibians and other species that cannot be found anywhere else in the world. On a cruise of the Galapagos, which means "saddle" and is so named for the shape of a tortoise shell, a naturalist is typically on board to introduce to you to many fascinating creatures.

Snap photos of unusual iguanas, sea cucumbers, flightless cormorants, sea lions, the blue-footed booby and the only living tropical penguin as you explore the islands. Conserving this ecological treasure is key at the Galapagos, so you will learn how scientists study its ecosystem and how they work to preserve its pristine condition. Take nature walks and short hikes to view not only the incredible wildlife, but the plants, flowers and volcanic rock as well. For travelers who enjoy snorkeling, the Galapagos is an amazing place to see underwater marine life.

Other cruises that touch South America include itineraries from the east coast of the United States to the west coast (or vice versa) that pass through the Panama Canal. A popular port of call is Cartagena, Columbia. Here, visit the impressive Castillo San Felipe de Barajas - an imposing fortress set on a hill that dates back to the 16th century.

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