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Panama Canal Cruises from San Diego, California

Save up to 75% on Panama Canal Cruises from San Diego, California

As a large-scale seller of Panama Canal Cruises from San Diego, California, we are able to offer you unbeatable prices and unparalleled value. With cruise line volume buys plus our low everyday prices you can save up to 80% versus the brochure price! Once you have found the discounted Panama Canal cruise of your choice, please call our cruise consultants to book your vacation and save money with our first-rate personalized service! Book your Panama Canal cruise today with AffordableTours.com, your discounted cruise headquarters. Learn more about Panama Canal Tours


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Sail Date Cruise Line Ship Destination Departs Length Price You Save Discounts
56 reviews
Itinerary Map/Ship Image
Holland AmericaVolendamPanama CanalSan DiegoFt. Lauderdale19 NightsCorinto, Nicaragua | Ft. Lauderdale, Florida | Fuerte Amador, Panama | Half Moon Cay, Bahamas | Huatulco, Mexico | Oranjestad, Aruba | Puerto Caldera, Costa Rica | Puerto Chiapas, Mexico | Puerto Quetzal, Guatemala | Puerto Vallarta, Mexico | Quepos, Costa Rica | San Diego, California$1,749
Up To $200 Onboard Credit
Onboard Credit!
78 reviews
Itinerary Map/Ship Image
Disney WonderPanama CanalSan DiegoGalveston14 NightsCabo San Lucas, Mexico | Cartagena, Colombia | Cozumel, Mexico | Galveston, TX | Grand Cayman, Cayman Islands | Puerto Vallarta, Mexico | San Diego, CA $2,142
Up To $500 Onboard Credit
Onboard Credit!
128 reviews
Itinerary Map/Ship Image
Celebrity SummitPanama CanalSan DiegoFt. Lauderdale15 NightsCabo San Lucas - Mexico | Cartagena - Colombia | Colon - Panama | Fort Lauderdale - Florida | Panama Canal (cruising) | Puerto Quetzal - Guatemala | Puerto Vallarta - Mexico | Puntarenas - Costa Rica | San Diego - California$1,249
Up To $250 Onboard Credit
***
83 reviews
Itinerary Map/Ship Image
Holland AmericaZaandamPanama CanalSan DiegoFt. Lauderdale14 NightsCartagena, Colombia | Ft. Lauderdale, Florida | Fuerte Amador, Panama | Huatulco, Mexico | Puerto Caldera, Costa Rica | Puerto Vallarta, Mexico | San Diego, California$1,349
Up To $200 Onboard Credit
Onboard Credit!

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83 reviews
Itinerary Map/Ship Image
Holland AmericaZaandamPanama CanalSan DiegoFt. Lauderdale18 NightsCartagena, Colombia | Corinto, Nicaragua | Ft. Lauderdale, Florida | Fuerte Amador, Panama | George Town, Grand Cayman | Huatulco, Mexico | Manzanillo, Mexico | Puerto Caldera, Costa Rica | Puerto Chiapas, Mexico | Puerto Quetzal, Guatemala | Puerto Vallarta, Mexico | San Diego, California$1,899
Up To $250 Onboard Credit
Onboard Credit!
158 reviews
Itinerary Map/Ship Image
PrincessEmerald PrincessPanama CanalSan DiegoFt. Lauderdale15 NightsCabo San Lucas, Mexico | Cartagena, Colombia | Ft. Lauderdale, Florida | Huatulco, Mexico | Puerto Amador, Panama | Puerto Vallarta, Mexico | Puntarenas, Costa Rica | San Diego, California | San Juan, Nicaragua$1,649
Up To $300 Onboard Credit
Onboard Credit!
83 reviews
Itinerary Map/Ship Image
Holland AmericaZaandamPanama CanalSan DiegoFt. Lauderdale18 NightsCartagena, Colombia | Corinto, Nicaragua | Ft. Lauderdale, Florida | Fuerte Amador, Panama | George Town, Grand Cayman | Huatulco, Mexico | Manzanillo, Mexico | Puerto Caldera, Costa Rica | Puerto Chiapas, Mexico | Puerto Quetzal, Guatemala | Puerto Vallarta, Mexico | San Diego, California$1,849
Up To $200 Onboard Credit
 
140 reviews
Itinerary Map/Ship Image
Holland AmericaEurodamPanama CanalSan DiegoFt. Lauderdale17 NightsCorinto, Nicaragua | Curacao, Netherlands | Ft. Lauderdale, Florida | Half Moon Cay, Bahamas | Huatulco, Mexico | Oranjestad, Aruba | Puerto Caldera, Costa Rica | Puerto Quetzal, Guatemala | Puerto Vallarta, Mexico | San Diego, California$2,199
Up To $500 Onboard Credit
Onboard Credit!
90 reviews
Itinerary Map/Ship Image
Holland AmericaNieuw AmsterdamPanama CanalSan DiegoFt. Lauderdale17 NightsCorinto, Nicaragua | Curacao, Netherlands | Ft. Lauderdale, Florida | Half Moon Cay, Bahamas | Huatulco, Mexico | Oranjestad, Aruba | Puerto Caldera, Costa Rica | Puerto Quetzal, Guatemala | Puerto Vallarta, Mexico | San Diego, California$2,199
Up To $500 Onboard Credit
Onboard Credit!
95 reviews
Itinerary Map/Ship Image
Celebrity MillenniumPanama CanalSan DiegoFt. Lauderdale15 NightsCabo San Lucas, Mexico | Cartagena, Colombia | Colon, Panama | Ft. Lauderdale, Florida | Panama Canal | Puerto Quetzal, Guatemala | Puerto Vallarta, Mexico | Puntarenas, Costa Rica | San Diego, California$1,759
$50 Onboard Credit
$50 Onboard Credit per Stateroom
83 reviews
Itinerary Map/Ship Image
Holland AmericaZaandamPanama CanalSan DiegoFt. Lauderdale14 NightsCartagena, Colombia | Corinto, Nicaragua | Ft. Lauderdale, Florida | Huatulco, Mexico | Puerto Caldera, Costa Rica | Puerto Quetzal, Guatemala | Puerto Vallarta, Mexico | San Diego, California
-100%
From: $9,999,999
You Save: $9,998,400
Up To $200 Onboard Credit
Onboard Credit!
104 reviews
Itinerary Map/Ship Image
Norwegian JewelPanama CanalSan DiegoPanama City11 NightsAcajutla, El Salvador | Cabo San Lucas, Mexico | Panama City (colon), Panama | Puerto Caldera (puntarenas), Costa Rica | Puerto Quetzal, Guatemala | San Diego, CA | San Juan Del Sur, Nicaragua | Transit Panama Canal, At Sea
-44%
From: $1,689
You Save: $750
Up To $150 Onboard Credit
44%
Onboard Credit!
56 reviews
Itinerary Map/Ship Image
Holland AmericaVolendamPanama CanalSan DiegoFt. Lauderdale18 NightsCartagena, Colombia | Corinto, Nicaragua | Ft. Lauderdale, Florida | Fuerte Amador, Panama | Half Moon Cay, Bahamas | Huatulco, Mexico | Manzanillo, Mexico | Puerto Caldera, Costa Rica | Puerto Chiapas, Mexico | Puerto Quetzal, Guatemala | Puerto Vallarta, Mexico | San Diego, California$1,999
Up To $250 Onboard Credit
Onboard Credit!

Learn More About Panama Canal Cruises

Sometimes called the Eighth Wonder of the World, the Panama Canal and its ingenious system of locks is an engineering feat. When construction was completed in 1914, vessels could sail conveniently from the Atlantic Ocean to the Pacific Ocean (and vice versa) through the Isthmus of Panama without having to take the incredibly time-consuming journey all the way around the tip of South America.

The Panama Canal is comprised of several artificial lakes, channels and reservoirs, and three lock systems. It takes a typical cruise ship about eight hours to make the journey from one ocean to the other. Cruising passengers remain onboard to marvel at the impressive engineering while their ship is raised and lowered through the locks. Along the way, passengers can admire other boats-from pleasure yachts to enormous cargo ships-as they make the journey, too. Scenic vistas are plentiful, with the lush jungle and countryside that surround the many lakes.

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