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South America Cruises from Santiago, Chile

Save up to 75% on South America Cruises from Santiago, Chile

As a large-scale seller of South America Cruises from Santiago, Chile, we are able to offer you unbeatable prices and unparalleled value. With cruise line volume buys plus our low everyday prices you can save up to 75% versus the brochure price! Once you have found the discounted South America cruise of your choice, please call our cruise consultants to book your vacation and save money with our first-rate personalized service! Book your South America cruise today with AffordableTours.com, your discounted cruise headquarters.

Learn more about South America Cruises

Cruises

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Sail Date Cruise Line Ship Destination Departs Length Price You Save Discounts
128 reviews
Itinerary Map/Ship Image
PrincessCoral PrincessSouth AmericaSantiagoRoad Town20 NightsBuenos Aires, Argentina | Rio De Janeiro, Brazil$6,390
Up To $750 Onboard Credit
Onboard Credit!
128 reviews
Itinerary Map/Ship Image
PrincessCoral PrincessSouth AmericaSantiagoRio De Janeiro21 NightsBuenos Aires, Argentina | Rio De Janeiro, Brazil$6,839
Up To $750 Onboard Credit
Onboard Credit!
128 reviews
Itinerary Map/Ship Image
PrincessCoral PrincessSouth AmericaSantiagoRio De Janeiro19 NightsBuenos Aires, Argentina | Rio De Janeiro, Brazil$6,337
Up To $750 Onboard Credit
Onboard Credit!
128 reviews
Itinerary Map/Ship Image
PrincessCoral PrincessSouth AmericaSantiagoRio De Janeiro19 NightsBuenos Aires, Argentina | Rio De Janeiro, Brazil$6,298
Up To $750 Onboard Credit
Onboard Credit!

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68 reviews
Itinerary Map/Ship Image
PrincessDiamond PrincessSouth AmericaSantiagoBuenos Aires22 NightsLima, Peru | San Antonio, Chile | Santiago, Chile$7,138
Up To $1000 Onboard Credit
Onboard Credit!
31 reviews
Itinerary Map/Ship Image
RegentSeven Seas NavigatorSouth AmericaSantiagoMiami18 NightsArica | Coquimbo | Costa Maya | Cozumel | Harvest Caye | Lima (Callao) | Manta | Miami | Puerto Limon | Roatan | Salaverry
-68%
From: $26,798
You Save: $18,099
$400 Onboard Credit
67%$400 Onboard Credit per Stateroom
68 reviews
Itinerary Map/Ship Image
PrincessDiamond PrincessAntarcticaSantiagoBuenos Aires16 NightsAntarctica Peninsula | Buenos Aires, Argentina | Cape Horn, Chile | Montevideo, Uruguay | Port Stanley, Falkland Islands | Punta Arenas, Chile | Santiago, Chile | Ushuaia, Argentina$2,548
Up To $500 Onboard Credit
 
68 reviews
Itinerary Map/Ship Image
PrincessDiamond PrincessSouth AmericaSantiagoBuenos Aires22 NightsLima, Peru | San Antonio, Chile | Santiago, Chile$7,138
Up To $1000 Onboard Credit
Onboard Credit!
68 reviews
Itinerary Map/Ship Image
PrincessDiamond PrincessAntarcticaSantiagoBuenos Aires16 NightsAntarctica Peninsula | Buenos Aires, Argentina | Cape Horn, Chile | Montevideo, Uruguay | Port Stanley, Falkland Islands | Punta Arenas, Chile | Santiago, Chile | Ushuaia, Argentina$2,548
Up To $500 Onboard Credit
Onboard Credit!
68 reviews
Itinerary Map/Ship Image
PrincessDiamond PrincessSouth AmericaSantiagoBuenos Aires21 NightsBuenos Aires, Argentina | Rio De Janeiro, Brazil$6,938
Up To $1000 Onboard Credit
Onboard Credit!
80 reviews
Itinerary Map/Ship Image
OceaniaMarinaSouth AmericaSantiagoBuenos Aires17 NightsBuenos Aires | Laguna San Rafael | Montevideo | Port Stanley | Puerto Chacabuco | Puerto Montt | Punta Arenas | Punta Del Este | Ushuaia
-78%
From: $15,598
You Save: $12,099
Up To $325 Onboard Credit
77%
Onboard Credit!
80 reviews
Itinerary Map/Ship Image
OceaniaMarinaSouth AmericaSantiagoRio De Janeiro29 NightsBuenos Aires | Buzios | Ilha Grande | Laguna San Rafael | Montevideo | Parati | Port Stanley | Porto Belo | Puerto Chacabuco | Puerto Montt | Punta Arenas | Punta Del Este | Rio De Janeiro | Rio Grande | Sao Paulo (santos) | Ushuaia
-74%
From: $25,498
You Save: $18,799
Up To $550 Onboard Credit
73% 
80 reviews
Itinerary Map/Ship Image
OceaniaMarinaSouth AmericaSantiagoMiami50 NightsAlter Do Chao (amazon River) | Boca Da Valeria (amazon River) | Buenos Aires | Buzios | Castries | Gustavia | Ilha Grande | Laguna San Rafael | Maceio | Manaus (amazon River) | Miami | Montevideo | Parati | Parintins (amazon River) | Port Stanley | Porto Belo | Puerto Chacabuco | Puerto Montt | Punta Arenas | Punta Del Este | Recife | Rio De Janeiro | Rio Grande | Santarem (amazon River) | Sao Paulo (santos) | Ushuaia
-70%
From: $44,498
You Save: $31,299
Up To $950 Onboard Credit
70%
Balcony!
31 reviews
Itinerary Map/Ship Image
RegentSeven Seas VoyagerSouth AmericaSantiagoBuenos Aires19 NightsBuenos Aires | Laguna San Rafael | Montevideo | Puerto Chacabuco | Puerto Montt | Punta Arenas | Stanley | Ushuaia
-66%
From: $39,598
You Save: $26,199
$400 Onboard Credit
66%$400 Onboard Credit per Stateroom
31 reviews
Itinerary Map/Ship Image
RegentSeven Seas VoyagerSouth AmericaSantiagoRio De Janeiro29 NightsBuenos Aires | Buzios | Ilha Grande | Laguna San Rafael | Montevideo | Porto Belo | Puerto Chacabuco | Puerto Montt | Punta Arenas | Rio De Janeiro | Rio Grande | Sao Paulo (Santos) | Stanley | Ushuaia
-65%
From: $55,798
You Save: $36,399
Up To $1000 Onboard Credit
65% 
Itinerary Map/Ship ImagePrincessDiscovery PrincessSouth AmericaSantiagoLos Angeles (San Pedro)24 NightsLima, Peru | San Antonio, Chile | Santiago, Chile$7,048
Up To $1000 Onboard Credit
 
Itinerary Map/Ship ImagePrincessDiscovery PrincessSouth AmericaSantiagoLos Angeles (San Pedro)18 NightsCabo San Lucas, Mexico | Callao, Peru | Coquimbo La Serena, Chile | Los Angeles (San Pedro) | Puerto Quetzal, Guatemala | Puerto San Martin, Peru | Puerto Vallarta, Mexico | Santiago, Chile$2,379
$75 SBC/Stateroom, $10 SBC/Stateroom
$75 SBC/Stateroom, $10 SBC/Stateroom
68 reviews
Itinerary Map/Ship Image
PrincessDiamond PrincessSouth AmericaSantiagoBuenos Aires20 NightsLima, Peru | San Antonio, Chile | Santiago, Chile$6,478
Up To $750 Onboard Credit
Onboard Credit!
68 reviews
Itinerary Map/Ship Image
PrincessDiamond PrincessSouth AmericaSantiagoBuenos Aires14 NightsAmalia Glacier,Chile | Buenos Aires, Argentina | Cape Horn, Chile | Montevideo, Uruguay | Port Stanley, Falkland Islands | Puerto Madryn, Argentina | Puerto Montt, Chile | Punta Arenas, Chile | Santiago, Chile | Ushuaia, Argentina$1,968
Up To $300 Onboard Credit
 
68 reviews
Itinerary Map/Ship Image
PrincessDiamond PrincessSouth AmericaSantiagoBuenos Aires19 NightsBuenos Aires, Argentina | Rio De Janeiro, Brazil$6,278
Up To $750 Onboard Credit
 

Learn More About South America Cruises

One incredibly popular South America cruise itinerary is to the Galapagos Islands, situated around the equator about 600 miles off the coast of continental Ecuador. Here reside dozens of birds, reptiles, amphibians and other species that cannot be found anywhere else in the world. On a cruise of the Galapagos, which means "saddle" and is so named for the shape of a tortoise shell, a naturalist is typically on board to introduce to you to many fascinating creatures.

Snap photos of unusual iguanas, sea cucumbers, flightless cormorants, sea lions, the blue-footed booby and the only living tropical penguin as you explore the islands. Conserving this ecological treasure is key at the Galapagos, so you will learn how scientists study its ecosystem and how they work to preserve its pristine condition. Take nature walks and short hikes to view not only the incredible wildlife, but the plants, flowers and volcanic rock as well. For travelers who enjoy snorkeling, the Galapagos is an amazing place to see underwater marine life.

Other cruises that touch South America include itineraries from the east coast of the United States to the west coast (or vice versa) that pass through the Panama Canal. A popular port of call is Cartagena, Columbia. Here, visit the impressive Castillo San Felipe de Barajas - an imposing fortress set on a hill that dates back to the 16th century.

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