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South America Cruises from Santos (Sao Paulo), Brazil

Save up to 75% on South America Cruises from Santos (Sao Paulo), Brazil

As a large-scale seller of South America Cruises from Santos (Sao Paulo), Brazil, we are able to offer you unbeatable prices and unparalleled value. With cruise line volume buys plus our low everyday prices you can save up to 75% versus the brochure price! Once you have found the discounted South America cruise of your choice, please call our cruise consultants to book your vacation and save money with our first-rate personalized service! Book your South America cruise today with AffordableTours.com, your discounted cruise headquarters.

Learn more about South America Cruises

Cruises

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Sail Date Cruise Line Ship Destination Departs Length Price You Save Discounts
14 reviews
Itinerary Map/Ship Image
MSC PreziosaSouth AmericaSantos (Sao Paulo)Santos (Sao Paulo)4 NightsBuzios, Brazil | Ilha Grande, Brazil | Santos, Brazil$379
Up To $50 Onboard Credit
Onboard Credit!
14 reviews
Itinerary Map/Ship Image
MSC PreziosaSouth AmericaSantos (Sao Paulo)Santos (Sao Paulo)3 NightsBalneario Camboriu, Brazil | Porto Belo, Brazil | Santos, Brazil$319
Up To $50 Onboard Credit
Onboard Credit!
14 reviews
Itinerary Map/Ship Image
MSC PreziosaSouth AmericaSantos (Sao Paulo)Santos (Sao Paulo)3 NightsBuzios, Brazil | Ilha Grande, Brazil | Santos, Brazil$279
Up To $50 Onboard Credit
 
14 reviews
Itinerary Map/Ship Image
MSC PreziosaSouth AmericaSantos (Sao Paulo)Santos (Sao Paulo)3 NightsBalneario Camboriu, Brazil | Porto Belo, Brazil | Santos, Brazil$319
Up To $50 Onboard Credit
 

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14 reviews
Itinerary Map/Ship Image
MSC PreziosaSouth AmericaSantos (Sao Paulo)Santos (Sao Paulo)3 NightsBuzios, Brazil | Ilha Grande, Brazil | Santos, Brazil$319
Up To $50 Onboard Credit
 
5 reviews
Itinerary Map/Ship Image
MSC SeaviewSouth AmericaSantos (Sao Paulo)Maceio4 NightsIlha Grande, Brazil | Maceio, Brazil | Salvador, Brazil | Santos, Brazil$329
Up To $50 Onboard Credit
 
5 reviews
Itinerary Map/Ship Image
MSC SeaviewSouth AmericaSantos (Sao Paulo)Salvador De Bahia3 NightsIlha Grande, Brazil | Salvador, Brazil | Santos, Brazil$309
Up To $50 Onboard Credit
Onboard Credit!
5 reviews
Itinerary Map/Ship Image
MSC SeaviewSouth AmericaSantos (Sao Paulo)Santos (Sao Paulo)7 NightsBuzios, Brazil | Ilha Grande, Brazil | Maceio, Brazil | Salvador, Brazil | Santos, Brazil$559
Up To $75 Onboard Credit
 
14 reviews
Itinerary Map/Ship Image
MSC PreziosaSouth AmericaSantos (Sao Paulo)Rio De Janeiro4 NightsIlhabela, Brazil | Rio de Janeiro, Brazil | Santos, Brazil$299
Up To $50 Onboard Credit
Onboard Credit!
5 reviews
Itinerary Map/Ship Image
MSC SeaviewSouth AmericaSantos (Sao Paulo)Santos (Sao Paulo)7 NightsBuzios, Brazil | Ilha Grande, Brazil | Maceio, Brazil | Salvador, Brazil | Santos, Brazil$539
Up To $75 Onboard Credit
Onboard Credit!
5 reviews
Itinerary Map/Ship Image
MSC SeaviewSouth AmericaSantos (Sao Paulo)Santos (Sao Paulo)7 NightsBuzios, Brazil | Ilha Grande, Brazil | Maceio, Brazil | Salvador, Brazil | Santos, Brazil$539
Up To $75 Onboard Credit
 
23 reviews
Itinerary Map/Ship Image
MSC MusicaSouth AmericaSantos (Sao Paulo)Santos (Sao Paulo)7 NightsBuenos Aires, Argentina | Itajai, Brazil | Punta Del Este, Uruguay | Santos, Brazil$519
Up To $75 Onboard Credit
Onboard Credit!
5 reviews
Itinerary Map/Ship Image
MSC SeaviewSouth AmericaSantos (Sao Paulo)Santos (Sao Paulo)7 NightsBuzios, Brazil | Ilha Grande, Brazil | Maceio, Brazil | Salvador, Brazil | Santos, Brazil$659
Up To $100 Onboard Credit
Onboard Credit!
23 reviews
Itinerary Map/Ship Image
MSC MusicaSouth AmericaSantos (Sao Paulo)Santos (Sao Paulo)7 NightsBuenos Aires, Argentina | Itajai, Brazil | Montevideo, Uruguay | Santos, Brazil$559
Up To $75 Onboard Credit
 
5 reviews
Itinerary Map/Ship Image
MSC SeaviewSouth AmericaSantos (Sao Paulo)Santos (Sao Paulo)7 NightsBuzios, Brazil | Copacabana, Brazil | Salvador, Brazil | Santos, Brazil$1,119
Up To $200 Onboard Credit
Onboard Credit!
23 reviews
Itinerary Map/Ship Image
MSC MusicaSouth AmericaSantos (Sao Paulo)Santos (Sao Paulo)7 NightsBuenos Aires, Argentina | Itajai, Brazil | Punta Del Este, Uruguay | Santos, Brazil$939
Up To $150 Onboard Credit
Onboard Credit!
5 reviews
Itinerary Map/Ship Image
MSC SeaviewSouth AmericaSantos (Sao Paulo)Santos (Sao Paulo)7 NightsBuzios, Brazil | Ilha Grande, Brazil | Maceio, Brazil | Salvador, Brazil | Santos, Brazil$639
Up To $100 Onboard Credit
Onboard Credit!
23 reviews
Itinerary Map/Ship Image
MSC MusicaSouth AmericaSantos (Sao Paulo)Santos (Sao Paulo)7 NightsBuenos Aires, Argentina | Itajai, Brazil | Punta Del Este, Uruguay | Santos, Brazil$519
Up To $100 Onboard Credit
Onboard Credit!
5 reviews
Itinerary Map/Ship Image
MSC SeaviewSouth AmericaSantos (Sao Paulo)Santos (Sao Paulo)7 NightsBuzios, Brazil | Ilha Grande, Brazil | Maceio, Brazil | Salvador, Brazil | Santos, Brazil$639
Up To $100 Onboard Credit
 
23 reviews
Itinerary Map/Ship Image
MSC MusicaSouth AmericaSantos (Sao Paulo)Santos (Sao Paulo)7 NightsBuenos Aires, Argentina | Itajai, Brazil | Punta Del Este, Uruguay | Santos, Brazil$519
Up To $100 Onboard Credit
Onboard Credit!

Learn More About South America Cruises

One incredibly popular South America cruise itinerary is to the Galapagos Islands, situated around the equator about 600 miles off the coast of continental Ecuador. Here reside dozens of birds, reptiles, amphibians and other species that cannot be found anywhere else in the world. On a cruise of the Galapagos, which means "saddle" and is so named for the shape of a tortoise shell, a naturalist is typically on board to introduce to you to many fascinating creatures.

Snap photos of unusual iguanas, sea cucumbers, flightless cormorants, sea lions, the blue-footed booby and the only living tropical penguin as you explore the islands. Conserving this ecological treasure is key at the Galapagos, so you will learn how scientists study its ecosystem and how they work to preserve its pristine condition. Take nature walks and short hikes to view not only the incredible wildlife, but the plants, flowers and volcanic rock as well. For travelers who enjoy snorkeling, the Galapagos is an amazing place to see underwater marine life.

Other cruises that touch South America include itineraries from the east coast of the United States to the west coast (or vice versa) that pass through the Panama Canal. A popular port of call is Cartagena, Columbia. Here, visit the impressive Castillo San Felipe de Barajas - an imposing fortress set on a hill that dates back to the 16th century.

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